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[Translated article] Paradoxical interaction between nirmatrelvir/ritonavir and voriconazole in a patient with COVID-19

This case is based on a drug interaction between nirmatrelvir/ritonavir (approved drug for COVID-19) and voriconazole is presented, possibly derived from the bidirectional effect of ritonavir on the 2 main voriconazole metabolizing enzymes (cytochrome P450 3A and 2C19) ritonavir inhibits the former...

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Detalles Bibliográficos
Autores principales: Herranz Bayo, Elena, Merchante Andreu, Miriam, Huarte Lacunza, Rafael, Aguiló Lafarga, Irene, Abad Sazatornil, MªReyes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Farmacia Hospitalaria (S.E.F.H). Published by Elsevier España, S.L.U. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941306/
https://www.ncbi.nlm.nih.gov/pubmed/36959068
http://dx.doi.org/10.1016/j.farma.2023.02.003

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