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The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

Behaviour is the response of living things to their environment and external stimulation, and is one of the parameters to be observed when assessing animal welfare. Any alteration from the conditions found in nature can lead to the occurrence of some specific behaviours, called stereotypies which ar...

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Autores principales: Cunha, Rodrigo Zamith, Felisardo, Letícia Locatelli, Salamanca, Giulia, Marchioni, Gabriela Gomes, Neto, Orlando Iazzetti, Chiocchetti, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941357/
https://www.ncbi.nlm.nih.gov/pubmed/36824298
http://dx.doi.org/10.1016/j.vas.2023.100289
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author Cunha, Rodrigo Zamith
Felisardo, Letícia Locatelli
Salamanca, Giulia
Marchioni, Gabriela Gomes
Neto, Orlando Iazzetti
Chiocchetti, Roberto
author_facet Cunha, Rodrigo Zamith
Felisardo, Letícia Locatelli
Salamanca, Giulia
Marchioni, Gabriela Gomes
Neto, Orlando Iazzetti
Chiocchetti, Roberto
author_sort Cunha, Rodrigo Zamith
collection PubMed
description Behaviour is the response of living things to their environment and external stimulation, and is one of the parameters to be observed when assessing animal welfare. Any alteration from the conditions found in nature can lead to the occurrence of some specific behaviours, called stereotypies which are characterised as repetitive, consistent patterns of behaviour usually defined as having no apparent ultimate or proximal functions. It has been reported that once stabled or subjected to stressful activities, horses have more susceptibility of developing behavioural disturbances; therefore, behavioural disorders in horses are a strong indicator of poor welfare. Cannabis spp.-derived molecules have been studied under different medical conditions; the therapeutic potentials of phytocannabinoids are related to the effects of delta-9-tetrahydrocannabinol, cannabidiol (CBD), and other compounds. Cannabidiol has many activities within the central nervous system, such as anxiolytic, antidepressant, antipsychotic, anticonvulsant, and anti-inflammatory activities. Some studies have recently shown the potential and successful therapeutic use of phytocannabinoids in veterinary medicine. This clinical case report described a 22-year-old mare suffering from chronic crib-biting and wind-sucking, and the successful outcome of four weeks-therapy with CBD. This is the first report of the successful therapeutic use of phytocannabinoids in equine behavioural disorders.
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spelling pubmed-99413572023-02-22 The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse Cunha, Rodrigo Zamith Felisardo, Letícia Locatelli Salamanca, Giulia Marchioni, Gabriela Gomes Neto, Orlando Iazzetti Chiocchetti, Roberto Vet Anim Sci Case Report Behaviour is the response of living things to their environment and external stimulation, and is one of the parameters to be observed when assessing animal welfare. Any alteration from the conditions found in nature can lead to the occurrence of some specific behaviours, called stereotypies which are characterised as repetitive, consistent patterns of behaviour usually defined as having no apparent ultimate or proximal functions. It has been reported that once stabled or subjected to stressful activities, horses have more susceptibility of developing behavioural disturbances; therefore, behavioural disorders in horses are a strong indicator of poor welfare. Cannabis spp.-derived molecules have been studied under different medical conditions; the therapeutic potentials of phytocannabinoids are related to the effects of delta-9-tetrahydrocannabinol, cannabidiol (CBD), and other compounds. Cannabidiol has many activities within the central nervous system, such as anxiolytic, antidepressant, antipsychotic, anticonvulsant, and anti-inflammatory activities. Some studies have recently shown the potential and successful therapeutic use of phytocannabinoids in veterinary medicine. This clinical case report described a 22-year-old mare suffering from chronic crib-biting and wind-sucking, and the successful outcome of four weeks-therapy with CBD. This is the first report of the successful therapeutic use of phytocannabinoids in equine behavioural disorders. Elsevier 2023-02-07 /pmc/articles/PMC9941357/ /pubmed/36824298 http://dx.doi.org/10.1016/j.vas.2023.100289 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Cunha, Rodrigo Zamith
Felisardo, Letícia Locatelli
Salamanca, Giulia
Marchioni, Gabriela Gomes
Neto, Orlando Iazzetti
Chiocchetti, Roberto
The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title_full The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title_fullStr The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title_full_unstemmed The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title_short The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
title_sort use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941357/
https://www.ncbi.nlm.nih.gov/pubmed/36824298
http://dx.doi.org/10.1016/j.vas.2023.100289
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