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Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors

We designed a liquid biopsy (LB) platform employing low-pass whole genome sequencing (LP-WGS) and targeted sequencing of cell-free (cf) DNA from plasma to detect genome-wide copy number alterations (CNAs) and gene fusions in pediatric solid tumors. A total of 143 plasma samples were analyzed from 19...

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Detalles Bibliográficos
Autores principales:	Christodoulou, Eirini, Yellapantula, Venkata, O’Halloran, Katrina, Xu, Liya, Berry, Jesse L., Cotter, Jennifer A., Zdanowicz, Anya, Mascarenhas, Leo, Amatruda, James F., Ostrow, Dejerianne, Bootwalla, Moiz, Gai, Xiaowu, Navid, Fariba, Biegel, Jaclyn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941464/ https://www.ncbi.nlm.nih.gov/pubmed/36805676 http://dx.doi.org/10.1038/s41698-023-00357-0

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