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Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport

Perivascular spaces are important highways for fluid and solute transport in the brain enabling efficient waste clearance during sleep. However, the underlying mechanisms augmenting perivascular flow in sleep are unknown. Using two-photon imaging of naturally sleeping male mice we demonstrate sleep...

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Detalles Bibliográficos
Autores principales: Bojarskaite, Laura, Vallet, Alexandra, Bjørnstad, Daniel M., Gullestad Binder, Kristin M., Cunen, Céline, Heuser, Kjell, Kuchta, Miroslav, Mardal, Kent-Andre, Enger, Rune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941497/
https://www.ncbi.nlm.nih.gov/pubmed/36806170
http://dx.doi.org/10.1038/s41467-023-36643-5