Cargando…

Recent updates in click and computational chemistry for drug discovery and development

Drug discovery is a costly and time-consuming process with a very high failure rate. Recently, click chemistry and computer-aided drug design (CADD) represent popular areas for new drug development. Herein, we summarized the recent updates in click and computational chemistry for drug discovery and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Jiang Hong, Zhu, Xuan Zhe, Guo, Peng Yue, Rose, Peter, Liu, Xiao Tong, Liu, Xia, Zhu, Yi Zhun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941707/ https://www.ncbi.nlm.nih.gov/pubmed/36825226 http://dx.doi.org/10.3389/fchem.2023.1114970

Ejemplares similares

Click Chemistry in Natural Product Modification
por: Zhang, Xiang, et al.
Publicado: (2021)

Bio-click chemistry: a bridge between biocatalysis and click chemistry
por: Rodríguez, Diego F., et al.
Publicado: (2022)

Boronic acid based dynamic click chemistry: recent advances and emergent applications
por: Chatterjee, Saurav, et al.
Publicado: (2020)

Click Chemistry and Radiochemistry: An Update
por: Bauer, David, et al.
Publicado: (2023)

Facile fabrication of polymer network using click chemistry and their computational study
por: Ahmed, Md. Kausar, et al.
Publicado: (2021)

Click Chemistry and Multicomponent Reaction for Linker Diversification of Zinc Dipicolylamine-Based Drug Conjugates
por: Tsai, Ching-Hua, et al.
Publicado: (2022)

Problems and Solutions in Click Chemistry Applied to Drug Probes
por: Zhong, Weilong, et al.
Publicado: (2016)

Natural products in drug discovery and development: Synthesis and medicinal perspective of leonurine
por: Li, Zhaoyi, et al.
Publicado: (2022)

Correction: Recent updates in the discovery and development of novel antimalarial drug candidates
por: Okombo, John, et al.
Publicado: (2018)

Development of self-stratified antibacterial polymers via click chemistry
por: Peng, Kaimei, et al.
Publicado: (2019)

Cell–cell interactions via non-covalent click chemistry
por: Plumet, Chad, et al.
Publicado: (2021)

[3+2] click chemistry approach to tetrazine containing polymers
por: Chavez, David E., et al.
Publicado: (2022)

Thiol–ene click chemistry: a biocompatible way for orthogonal bioconjugation of colloidal nanoparticles
por: Liu, Yuan, et al.
Publicado: (2017)

Visualizing Lignification Dynamics in Plants with Click Chemistry: Dual Labeling is BLISS!
por: Simon, Clémence, et al.
Publicado: (2018)

Click-chemistry approaches to π-conjugated polymers for organic electronics applications
por: Marrocchi, Assunta, et al.
Publicado: (2016)

Synthesis of unsymmetrical sulfamides and polysulfamides via SuFEx click chemistry
por: Kulow, Ryan W., et al.
Publicado: (2020)

Recent Advances in Click Chemistry Applied to Dendrimer Synthesis
por: Arseneault, Mathieu, et al.
Publicado: (2015)

Alginate based antimicrobial hydrogels formed by integrating Diels–Alder “click chemistry” and the thiol–ene reaction
por: Wang, Gang, et al.
Publicado: (2018)

Functionalised thermally induced phase separation (TIPS) microparticles enabled for “click” chemistry
por: Nogueira, João C. F., et al.
Publicado: (2020)

Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo
por: Kim, Eunha, et al.
Publicado: (2019)

Chemoselective bioconjugation based on modular click chemistry with 4-halocoumarins and aryl sulfonates
por: Thanzeel, F. Yushra, et al.
Publicado: (2021)

Click Chemistry in Peptide-Based Drug Design
por: Li, Huiyuan, et al.
Publicado: (2013)

AutoClickChem: Click Chemistry in Silico
por: Durrant, Jacob D., et al.
Publicado: (2012)

Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents
por: McStay, Natasha, et al.
Publicado: (2021)

Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins
por: Raulf, Anika, et al.
Publicado: (2014)

Post synthetic exchange enables orthogonal click chemistry in a metal organic framework
por: Fluch, Ulrike, et al.
Publicado: (2019)

Click chemistry approaches to expand the repertoire of PEG-based fluorinated surfactants for droplet microfluidics
por: Scanga, Randall, et al.
Publicado: (2018)

Oxygen insensitive thiol–ene photo-click chemistry for direct imprint lithography of oxides
por: Nagarjuna, Ravikiran, et al.
Publicado: (2018)

A unimolecular DNA fluorescent probe for determination of copper ions based on click chemistry
por: Qin, Yingfeng, et al.
Publicado: (2020)

Plasmon-assisted click chemistry at low temperature: an inverse temperature effect on the reaction rate
por: Guselnikova, Olga, et al.
Publicado: (2021)

Chemistry of 3-cyanoacetyl indoles: synthesis, reactions and applications: a recent update
por: Olyaei, Abolfazl, et al.
Publicado: (2023)

Recent trends in click chemistry as a promising technology for virus-related research
por: Ouyang, Ting, et al.
Publicado: (2018)

Editorial: Discovery of Novel Molecules for Corrosion Protection Using Computational Chemistry
por: Obot, Ime B., et al.
Publicado: (2018)

Click chemistry and drug delivery: A bird's-eye view
por: Kondengadan, Shameer M., et al.
Publicado: (2023)

Frontiers in Computational Chemistry for Drug Discovery
por: Luque, F. Javier
Publicado: (2018)

Synthesis of Symmetrical Tetrameric Conjugates of the Radiolanthanide Chelator DOTPI for Application in Endoradiotherapy by Means of Click Chemistry
por: Wurzer, Alexander, et al.
Publicado: (2018)

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins
por: Hems, Edward S., et al.
Publicado: (2018)

Detecting hypoxia in vitro using (18)F-pretargeted IEDDA “click” chemistry in live cells
por: Allott, Louis, et al.
Publicado: (2021)

Correction: Click chemistry approaches to expand the repertoire of PEG-based fluorinated surfactants for droplet microfluidics
por: Scanga, Randall, et al.
Publicado: (2019)

Radiolabelling an (18)F biologic via facile IEDDA “click” chemistry on the GE FASTLab™ platform
por: Allott, Louis, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l0lcqb085jjfvtdos8btgs67ju