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Effect of Adjunctive Simvastatin on Depressive Symptoms Among Adults With Treatment-Resistant Depression: A Randomized Clinical Trial

IMPORTANCE: Immune-metabolic disturbances have been implicated in the pathophysiology of major depressive disorder and may be more prominent in individuals with treatment-resistant depression (TRD). Preliminary trials suggest that lipid-lowering agents, including statins, may be useful adjunctive tr...

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Detalles Bibliográficos
Autores principales: Husain, M. Ishrat, Chaudhry, Imran B., Khoso, Ameer B., Kiran, Tayyeba, Khan, Nawaz, Ahmad, Farooq, Hodsoll, John, Husain, M. Omair, Naqvi, Haider A., Nizami, Asad T., Chaudhry, Nasim, Khan, Hazrat A., Minhas, Fareed, Meyer, Jeffrey H., Ansari, Moin A., Mulsant, Benoit H., Husain, Nusrat, Young, Allan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941891/
https://www.ncbi.nlm.nih.gov/pubmed/36808239
http://dx.doi.org/10.1001/jamanetworkopen.2023.0147

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