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Effect of Adjunctive Simvastatin on Depressive Symptoms Among Adults With Treatment-Resistant Depression: A Randomized Clinical Trial
IMPORTANCE: Immune-metabolic disturbances have been implicated in the pathophysiology of major depressive disorder and may be more prominent in individuals with treatment-resistant depression (TRD). Preliminary trials suggest that lipid-lowering agents, including statins, may be useful adjunctive tr...
Autores principales: | Husain, M. Ishrat, Chaudhry, Imran B., Khoso, Ameer B., Kiran, Tayyeba, Khan, Nawaz, Ahmad, Farooq, Hodsoll, John, Husain, M. Omair, Naqvi, Haider A., Nizami, Asad T., Chaudhry, Nasim, Khan, Hazrat A., Minhas, Fareed, Meyer, Jeffrey H., Ansari, Moin A., Mulsant, Benoit H., Husain, Nusrat, Young, Allan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941891/ https://www.ncbi.nlm.nih.gov/pubmed/36808239 http://dx.doi.org/10.1001/jamanetworkopen.2023.0147 |
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