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Introducing electric field fabrication: A method of additive manufacturing via liquid dielectrophoresis

Biomedical devices with millimeter and micron-scaled features have been a promising approach to single-cell analysis, diagnostics, and fundamental biological and chemical studies. These devices, however, have not been able to fully embrace the advantages of additive manufacturing (AM) that offers qu...

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Detalles Bibliográficos
Autores principales: Duncan, Josie L., Schultz, Jeff, Barlow, Zeke, Davalos, Rafael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941962/
https://www.ncbi.nlm.nih.gov/pubmed/36814549
http://dx.doi.org/10.1016/j.addlet.2022.100107
Descripción
Sumario:Biomedical devices with millimeter and micron-scaled features have been a promising approach to single-cell analysis, diagnostics, and fundamental biological and chemical studies. These devices, however, have not been able to fully embrace the advantages of additive manufacturing (AM) that offers quick prototypes and complexities not achievable via traditional 2D fabrication techniques (e.g., soft lithography). This slow adoption of AM can be attributed in part to limited material selection, resolution, and inability to easily integrate components mid-print. Here, we present the feasibility of using liquid dielectrophoresis to manipulate and shape a droplet of build material, paired with subsequent curing and stacking, to generate 3D parts. This Electric Field Fabrication (EFF) technique is an additive manufacturing method that offers advantages such as new printable materials and mixed-media parts without post-assembly for biomedical applications.