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BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection

Basic leucine zipper ATF-like transcription factor 2 (BATF2), an interferon-activated immune response regulator, is a key factor responsible for myeloid differentiation and depletion of HSC during chronic infection. To delineate the mechanism of BATF2 function in HSCs, we assessed Batf2 KO mice duri...

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Detalles Bibliográficos
Autores principales: Le, Duy T., Florez, Marcus A., Kus, Pawel, Tran, Brandon T., Kain, Bailee, Zhu, Yingmin, Christensen, Kurt, Jain, Antrix, Malovannaya, Anna, King, Katherine Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942003/
https://www.ncbi.nlm.nih.gov/pubmed/36824275
http://dx.doi.org/10.1016/j.isci.2023.106059