Ruthenium-catalyzed hydroarylation reactions as the strategy towards the synthesis of alkylated arenes and substituted alkenes

Metal-catalyzed hydroarylation reactions are always powerful tools in organic synthesis since they can form C–C or C-heteroatom bonds in an atom and step economic manner. Medicinally and biologically relevant scaffolds can be easily and efficiently synthesized using this strategy. By tuning the directing groups that are present on the arenes, regioselectivity can be induced to the C–H activation. Metals like cobalt, rhodium and ruthenium are well known as catalysts in this type of reaction. But due to their easy availability and efficiency, Ru catalysts are found to be more preferable for hydroarylation purposes. In this review, the Ru-catalyzed hydroarylation of alkenes and alkynes, intramolecular Ru-catalyzed hydroarylation of olefin tethered arenes, modifications in the catalytic system to improve the catalytic efficiency, and carboxylate-assisted Ru-catalyzed hydroarylation reactions are discussed in detail, covering literature from 2016 to 2022.