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Bilateral primary angiosarcoma of the breast: a case report
BACKGROUND: Primary angiosarcoma of the breast is very rare, accounting for 0.05% of all malignant breast tumors. It has very high malignant potential and poor prognosis, though due to the rarity of the disease, there is no established treatment. We report this case along with a literature review. C...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942292/ https://www.ncbi.nlm.nih.gov/pubmed/36803941 http://dx.doi.org/10.1186/s13256-023-03791-7 |
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author | Ooe, Yuka Terakawa, Hirofumi Kawashima, Hiroko Ikeda, Hiroko Inaki, Noriyuki |
author_facet | Ooe, Yuka Terakawa, Hirofumi Kawashima, Hiroko Ikeda, Hiroko Inaki, Noriyuki |
author_sort | Ooe, Yuka |
collection | PubMed |
description | BACKGROUND: Primary angiosarcoma of the breast is very rare, accounting for 0.05% of all malignant breast tumors. It has very high malignant potential and poor prognosis, though due to the rarity of the disease, there is no established treatment. We report this case along with a literature review. CASE PRESENTATION: We report the case of a 30-year-old Asian woman who was diagnosed with bilateral primary angiosarcoma of the breast while breastfeeding. After surgery, she underwent radiation therapy, chemotherapy, and hepatic arterial infusion chemotherapy for local recurrence of liver metastases, but these were ineffective, and she required several arterial embolization procedures for intratumoral bleeding and rupture of liver metastases. CONCLUSIONS: Angiosarcoma has a poor prognosis due to a high rate of local recurrence and distant metastasis. Although there is no established evidence for radiotherapy or chemotherapy, multimodality treatment may be necessary because of the high malignancy and rapid progression of the disease. |
format | Online Article Text |
id | pubmed-9942292 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-99422922023-02-22 Bilateral primary angiosarcoma of the breast: a case report Ooe, Yuka Terakawa, Hirofumi Kawashima, Hiroko Ikeda, Hiroko Inaki, Noriyuki J Med Case Rep Case Report BACKGROUND: Primary angiosarcoma of the breast is very rare, accounting for 0.05% of all malignant breast tumors. It has very high malignant potential and poor prognosis, though due to the rarity of the disease, there is no established treatment. We report this case along with a literature review. CASE PRESENTATION: We report the case of a 30-year-old Asian woman who was diagnosed with bilateral primary angiosarcoma of the breast while breastfeeding. After surgery, she underwent radiation therapy, chemotherapy, and hepatic arterial infusion chemotherapy for local recurrence of liver metastases, but these were ineffective, and she required several arterial embolization procedures for intratumoral bleeding and rupture of liver metastases. CONCLUSIONS: Angiosarcoma has a poor prognosis due to a high rate of local recurrence and distant metastasis. Although there is no established evidence for radiotherapy or chemotherapy, multimodality treatment may be necessary because of the high malignancy and rapid progression of the disease. BioMed Central 2023-02-21 /pmc/articles/PMC9942292/ /pubmed/36803941 http://dx.doi.org/10.1186/s13256-023-03791-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Ooe, Yuka Terakawa, Hirofumi Kawashima, Hiroko Ikeda, Hiroko Inaki, Noriyuki Bilateral primary angiosarcoma of the breast: a case report |
title | Bilateral primary angiosarcoma of the breast: a case report |
title_full | Bilateral primary angiosarcoma of the breast: a case report |
title_fullStr | Bilateral primary angiosarcoma of the breast: a case report |
title_full_unstemmed | Bilateral primary angiosarcoma of the breast: a case report |
title_short | Bilateral primary angiosarcoma of the breast: a case report |
title_sort | bilateral primary angiosarcoma of the breast: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942292/ https://www.ncbi.nlm.nih.gov/pubmed/36803941 http://dx.doi.org/10.1186/s13256-023-03791-7 |
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