MYC promotes fibroblast osteogenesis by regulating ALP and BMP2 to participate in ectopic ossification of ankylosing spondylitis

BACKGROUND: Ectopic ossification is an important cause of disability in patients with ankylosing spondylitis (AS). Whether fibroblasts can transdifferentiate into osteoblasts and contribute to ossification remains unknown. This study aims to investigate the role of stem cell transcription factors (P...

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Detalles Bibliográficos
Autores principales: Jin, Qianmei, Liu, Yaoyang, Zhang, Zhiguo, Wen, Xingzhu, Chen, Ziqiang, Tian, Haijun, Kang, Zijian, Wu, Xin, Xu, Huji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942334/
https://www.ncbi.nlm.nih.gov/pubmed/36803548
http://dx.doi.org/10.1186/s13075-023-03011-z

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