Dishevelled 2 regulates cancer cell proliferation and T cell mediated immunity in HER2-positive breast cancer

BACKGROUND: Dishevelled paralogs (DVL1, 2, 3) are key mediators of Wnt pathway playing a role in constitutive oncogenic signaling influencing the tumor microenvironment. While previous studies showed correlation of β-catenin with T cell gene expression, little is known about the role of DVL2 in modu...

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Detalles Bibliográficos
Autores principales: Rasha, Fahmida, Boligala, Geetha Priya, Yang, Mingxiao V., Martinez-Marin, Dalia, Castro-Piedras, Isabel, Furr, Kathryn, Snitman, Annie, Khan, Sonia Y., Brandi, Luis, Castro, Maribel, Khan, Hafiz, Jahan, Nusrat, Almodovar, Sharilyn, Melkus, Michael W., Pruitt, Kevin, Layeequr Rahman, Rakhshanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942370/
https://www.ncbi.nlm.nih.gov/pubmed/36809986
http://dx.doi.org/10.1186/s12885-023-10647-2

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