Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice

BACKGROUND: Gut homeostasis, including intestinal immunity and microbiome, is essential for cognitive function via the gut-brain axis. This axis is altered in high-fat diet (HFD)-induced cognitive impairment and is closely associated with neurodegenerative diseases. Dimethyl itaconate (DI) is an ita...

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Detalles Bibliográficos
Autores principales: Pan, Wei, Zhao, Jinxiu, Wu, Jiacheng, Xu, Daxiang, Meng, Xianran, Jiang, Pengfei, Shi, Hongli, Ge, Xing, Yang, Xiaoying, Hu, Minmin, Zhang, Peng, Tang, Renxian, Nagaratnam, Nathan, Zheng, Kuiyang, Huang, Xu-Feng, Yu, Yinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942412/
https://www.ncbi.nlm.nih.gov/pubmed/36810115
http://dx.doi.org/10.1186/s40168-023-01471-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942412/
https://www.ncbi.nlm.nih.gov/pubmed/36810115
http://dx.doi.org/10.1186/s40168-023-01471-8

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