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Ineffectiveness of Crizotinib in a Non-Small-Cell Lung Cancer with Novel ALK- LIMS1 Fusion: A Case Report

Anaplastic lymphoma kinase (ALK) rearrangements have been reported in 3–7% of non-small-cell lung cancers (NSCLC). ALK has been reported to be fused with a variety of genes in NSCLC. Significant clinical activity was achieved by ALK inhibitors in patients with NSCLC harbouring ALK translocations. We...

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Detalles Bibliográficos
Autores principales: Shi, Junmei, Jia, Zhaohui, Zhou, Zhiguo, Zhao, Liyan, Meng, Qingju, Liu, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942507/
https://www.ncbi.nlm.nih.gov/pubmed/36824323
http://dx.doi.org/10.2147/OTT.S388962