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Utility of monocyte HLA-DR and rationale for therapeutic GM-CSF in sepsis immunoparalysis

Sepsis, a heterogeneous clinical syndrome, features a systemic inflammatory response to tissue injury or infection, followed by a state of reduced immune responsiveness. Measurable alterations occur in both the innate and adaptive immune systems. Immunoparalysis, an immunosuppressed state, associate...

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Detalles Bibliográficos
Autores principales: Joshi, Ila, Carney, Walter P., Rock, Edwin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942705/
https://www.ncbi.nlm.nih.gov/pubmed/36825018
http://dx.doi.org/10.3389/fimmu.2023.1130214