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Poorly differentiated thyroid carcinoma: An institutional experience

PURPOSE: The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features. METHODS: Data of PDTC patients from...

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Autores principales: Choi, Seok Won, Lee, Joon-Hyop, Kim, Yun Young, Chung, Yoo Seung, Choi, Sangtae, Kim, Na Rae, Kang, Jin Mo, Park, Heung Kyu, Chun, Yong Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Surgical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942713/
https://www.ncbi.nlm.nih.gov/pubmed/36945302
http://dx.doi.org/10.14216/kjco.20005
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author Choi, Seok Won
Lee, Joon-Hyop
Kim, Yun Young
Chung, Yoo Seung
Choi, Sangtae
Kim, Na Rae
Kang, Jin Mo
Park, Heung Kyu
Chun, Yong Soon
author_facet Choi, Seok Won
Lee, Joon-Hyop
Kim, Yun Young
Chung, Yoo Seung
Choi, Sangtae
Kim, Na Rae
Kang, Jin Mo
Park, Heung Kyu
Chun, Yong Soon
author_sort Choi, Seok Won
collection PubMed
description PURPOSE: The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features. METHODS: Data of PDTC patients from our institution are collected through the electronic medical database. We analyzed them by several parameters such as basic demographics, presenting symptom, preoperative cytology results, associated pathology, surgical results, surgery type, and distant metastasis. RESULTS: We collected 23 cases in our institution. Apart from two patients who were transferred to another hospital upon diagnosis, all 21 operated cases are analyzed. The parameters we studied were age, sex, presenting symptoms, distant metastasis and pathological features such as tumor size, associated pathology, predominant pattern and so on. We also provided descriptive analyses according to the type of presentation and treatment; patients with distant metastasis, juvenile cancer, and concurrent hyperthyroidism. Furthermore, we provided different cases in which the initial surgical plans differed. CONCLUSION: We present 21 cases of PDTC patients and clarify their clinicopathological features. Despite some limitations, this study may shed light for future research regarding treatment of PDTC patients.
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spelling pubmed-99427132023-03-20 Poorly differentiated thyroid carcinoma: An institutional experience Choi, Seok Won Lee, Joon-Hyop Kim, Yun Young Chung, Yoo Seung Choi, Sangtae Kim, Na Rae Kang, Jin Mo Park, Heung Kyu Chun, Yong Soon Korean J Clin Oncol Original Article PURPOSE: The incidence of poorly differentiated thyroid carcinoma (PDTC) is extremely low among thyroid cancers and there is no standardized treatment guideline for it. In this study, we have analyzed PDTC patients and reviewed their clinicopathological features. METHODS: Data of PDTC patients from our institution are collected through the electronic medical database. We analyzed them by several parameters such as basic demographics, presenting symptom, preoperative cytology results, associated pathology, surgical results, surgery type, and distant metastasis. RESULTS: We collected 23 cases in our institution. Apart from two patients who were transferred to another hospital upon diagnosis, all 21 operated cases are analyzed. The parameters we studied were age, sex, presenting symptoms, distant metastasis and pathological features such as tumor size, associated pathology, predominant pattern and so on. We also provided descriptive analyses according to the type of presentation and treatment; patients with distant metastasis, juvenile cancer, and concurrent hyperthyroidism. Furthermore, we provided different cases in which the initial surgical plans differed. CONCLUSION: We present 21 cases of PDTC patients and clarify their clinicopathological features. Despite some limitations, this study may shed light for future research regarding treatment of PDTC patients. Korean Society of Surgical Oncology 2020-06 2020-06-30 /pmc/articles/PMC9942713/ /pubmed/36945302 http://dx.doi.org/10.14216/kjco.20005 Text en Copyright © Korean Society of Surgical Oncology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Choi, Seok Won
Lee, Joon-Hyop
Kim, Yun Young
Chung, Yoo Seung
Choi, Sangtae
Kim, Na Rae
Kang, Jin Mo
Park, Heung Kyu
Chun, Yong Soon
Poorly differentiated thyroid carcinoma: An institutional experience
title Poorly differentiated thyroid carcinoma: An institutional experience
title_full Poorly differentiated thyroid carcinoma: An institutional experience
title_fullStr Poorly differentiated thyroid carcinoma: An institutional experience
title_full_unstemmed Poorly differentiated thyroid carcinoma: An institutional experience
title_short Poorly differentiated thyroid carcinoma: An institutional experience
title_sort poorly differentiated thyroid carcinoma: an institutional experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942713/
https://www.ncbi.nlm.nih.gov/pubmed/36945302
http://dx.doi.org/10.14216/kjco.20005
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