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Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma

PURPOSE: The extent of surgery necessary in patients with unilateral papillary thyroid carcinoma (PTC) on preoperative radiologic imaging is still in doubt. In this study, we aimed to define risk factors that could be indicators for malignant nodules in the contralateral thyroid lobe. METHODS: We in...

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Autores principales: Ahn, Ha Rim, Kang, Sang Yull, Youn, Hyun Jo, Jung, Sung Hoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Surgical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942722/
https://www.ncbi.nlm.nih.gov/pubmed/36945305
http://dx.doi.org/10.14216/kjco.20006
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author Ahn, Ha Rim
Kang, Sang Yull
Youn, Hyun Jo
Jung, Sung Hoo
author_facet Ahn, Ha Rim
Kang, Sang Yull
Youn, Hyun Jo
Jung, Sung Hoo
author_sort Ahn, Ha Rim
collection PubMed
description PURPOSE: The extent of surgery necessary in patients with unilateral papillary thyroid carcinoma (PTC) on preoperative radiologic imaging is still in doubt. In this study, we aimed to define risk factors that could be indicators for malignant nodules in the contralateral thyroid lobe. METHODS: We included 438 patients who underwent total thyroidectomy between January 2011 and December 2014 at our institution. In this study, patients were divided into two groups according to the presence of contralateral occult carcinoma identified by postoperative pathological examination. We analyzed the clinicopathologic factors including characteristics of coexistent nodules in the contralateral lobe based on preoperative radiological imaging. RESULTS: A total of 96 patients (21.9%) had PTC in the contralateral lobe. There were no significant differences between patients with or without contralateral occult carcinoma with respect to gender, age, primary tumor size, central lymph node metastasis, extrathyroidal extension and stage. The presence of Hashimoto’s thyroiditis was an independent predictive factor for contralateral occult carcinoma (P=0.01). CONCLUSION: A risk factor for contralateral occult carcinoma in unilateral PTC patients is Hashimoto’s thyroiditis. Therefore, more caution is needed when determining optimal surgical methods for PTC patients with Hashimoto’s thyroiditis.
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spelling pubmed-99427222023-03-20 Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma Ahn, Ha Rim Kang, Sang Yull Youn, Hyun Jo Jung, Sung Hoo Korean J Clin Oncol Original Article PURPOSE: The extent of surgery necessary in patients with unilateral papillary thyroid carcinoma (PTC) on preoperative radiologic imaging is still in doubt. In this study, we aimed to define risk factors that could be indicators for malignant nodules in the contralateral thyroid lobe. METHODS: We included 438 patients who underwent total thyroidectomy between January 2011 and December 2014 at our institution. In this study, patients were divided into two groups according to the presence of contralateral occult carcinoma identified by postoperative pathological examination. We analyzed the clinicopathologic factors including characteristics of coexistent nodules in the contralateral lobe based on preoperative radiological imaging. RESULTS: A total of 96 patients (21.9%) had PTC in the contralateral lobe. There were no significant differences between patients with or without contralateral occult carcinoma with respect to gender, age, primary tumor size, central lymph node metastasis, extrathyroidal extension and stage. The presence of Hashimoto’s thyroiditis was an independent predictive factor for contralateral occult carcinoma (P=0.01). CONCLUSION: A risk factor for contralateral occult carcinoma in unilateral PTC patients is Hashimoto’s thyroiditis. Therefore, more caution is needed when determining optimal surgical methods for PTC patients with Hashimoto’s thyroiditis. Korean Society of Surgical Oncology 2020-06 2020-06-30 /pmc/articles/PMC9942722/ /pubmed/36945305 http://dx.doi.org/10.14216/kjco.20006 Text en Copyright © Korean Society of Surgical Oncology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ahn, Ha Rim
Kang, Sang Yull
Youn, Hyun Jo
Jung, Sung Hoo
Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title_full Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title_fullStr Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title_full_unstemmed Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title_short Risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
title_sort risk factor for contralateral occult carcinoma in patients with unilateral papillary thyroid carcinoma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942722/
https://www.ncbi.nlm.nih.gov/pubmed/36945305
http://dx.doi.org/10.14216/kjco.20006
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