A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function

To fertilize an oocyte, the membrane potential of both mouse and human sperm must hyperpolarize (become more negative inside). Determining the molecular mechanisms underlying this hyperpolarization is vital for developing new contraceptive methods and detecting causes of idiopathic male infertility....

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Detalles Bibliográficos
Autores principales: Lyon, Maximilian, Li, Ping, Ferreira, Juan J., Lazarenko, Roman M., Kharade, Sujay V., Kramer, Meghan, McClenahan, Samantha J., Days, Emily, Bauer, Joshua A., Spitznagel, Brittany D., Weaver, C. David, Borrego Alvarez, Aluet, Puga Molina, Lis C., Lybaert, Pascale, Khambekar, Saayli, Liu, Alicia, Lindsley, Craig W., Denton, Jerod, Santi, Celia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942793/
https://www.ncbi.nlm.nih.gov/pubmed/36649421
http://dx.doi.org/10.1073/pnas.2212338120

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