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Enhancer–promoter entanglement explains their transcriptional interdependence
Enhancers not only activate target promoters to stimulate messenger RNA (mRNA) synthesis, but they themselves also undergo transcription to produce enhancer RNAs (eRNAs), the significance of which is not well understood. Transcription at the participating enhancer–promoter pair appears coordinated,...
Autores principales: | Panigrahi, Anil K., Lonard, David M., O’Malley, Bert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942820/ https://www.ncbi.nlm.nih.gov/pubmed/36656865 http://dx.doi.org/10.1073/pnas.2216436120 |
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