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Enhancer–promoter entanglement explains their transcriptional interdependence

Enhancers not only activate target promoters to stimulate messenger RNA (mRNA) synthesis, but they themselves also undergo transcription to produce enhancer RNAs (eRNAs), the significance of which is not well understood. Transcription at the participating enhancer–promoter pair appears coordinated,...

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Detalles Bibliográficos
Autores principales: Panigrahi, Anil K., Lonard, David M., O’Malley, Bert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942820/
https://www.ncbi.nlm.nih.gov/pubmed/36656865
http://dx.doi.org/10.1073/pnas.2216436120

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