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Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids
Nonvesicular extracellular RNAs (nv-exRNAs) constitute the majority of the extracellular RNAome, but little is known about their stability, function, and potential use as disease biomarkers. Herein, we measured the stability of several naked RNAs when incubated in human serum, urine, and cerebrospin...
Autores principales: | Costa, Bruno, Li Calzi, Marco, Castellano, Mauricio, Blanco, Valentina, Cuevasanta, Ernesto, Litvan, Irene, Ivanov, Pavel, Witwer, Kenneth, Cayota, Alfonso, Tosar, Juan Pablo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942843/ https://www.ncbi.nlm.nih.gov/pubmed/36652478 http://dx.doi.org/10.1073/pnas.2216330120 |
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