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Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming
Reactivation of the inactive X chromosome is a hallmark epigenetic event during reprogramming of mouse female somatic cells to induced pluripotent stem cells (iPSCs). This involves global structural remodeling from a condensed, heterochromatic into an open, euchromatic state, thereby changing a tran...
Autores principales: | Generoso, Serena F., Neguembor, Maria Victoria, Hershberg, Elliot A., Sadreyev, Ruslan I., Kurimoto, Kazuki, Yabuta, Yukihiro, Ricci, Raffaele, Audergon, Pauline, Bauer, Moritz, Saitou, Mitinori, Hochedlinger, Konrad, Beliveau, Brian J., Cosma, Maria Pia, Lee, Jeannie T., Payer, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942853/ https://www.ncbi.nlm.nih.gov/pubmed/36669113 http://dx.doi.org/10.1073/pnas.2213810120 |
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