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Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming

Reactivation of the inactive X chromosome is a hallmark epigenetic event during reprogramming of mouse female somatic cells to induced pluripotent stem cells (iPSCs). This involves global structural remodeling from a condensed, heterochromatic into an open, euchromatic state, thereby changing a tran...

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Detalles Bibliográficos
Autores principales: Generoso, Serena F., Neguembor, Maria Victoria, Hershberg, Elliot A., Sadreyev, Ruslan I., Kurimoto, Kazuki, Yabuta, Yukihiro, Ricci, Raffaele, Audergon, Pauline, Bauer, Moritz, Saitou, Mitinori, Hochedlinger, Konrad, Beliveau, Brian J., Cosma, Maria Pia, Lee, Jeannie T., Payer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942853/
https://www.ncbi.nlm.nih.gov/pubmed/36669113
http://dx.doi.org/10.1073/pnas.2213810120

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