Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

Granulomas are lumps of immune cells that can form in various organs. Most granulomas appear unstructured, yet they have some resemblance to lymphoid organs. To better understand granuloma formation, we performed single-cell sequencing and spatial transcriptomics on granulomas from patients with sar...

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Detalles Bibliográficos
Autores principales: Krausgruber, Thomas, Redl, Anna, Barreca, Daniele, Doberer, Konstantin, Romanovskaia, Daria, Dobnikar, Lina, Guarini, Maria, Unterluggauer, Luisa, Kleissl, Lisa, Atzmüller, Denise, Mayerhofer, Carolina, Kopf, Aglaja, Saluzzo, Simona, Lim, Clarice X., Rexie, Praveen, Weichhart, Thomas, Bock, Christoph, Stary, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942876/
https://www.ncbi.nlm.nih.gov/pubmed/36750099
http://dx.doi.org/10.1016/j.immuni.2023.01.014

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