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Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase

Mitotic entry correlates with the condensation of the chromosomes, changes in histone modifications, exclusion of transcription factors from DNA, and the broad downregulation of transcription. However, whether mitotic condensation influences transcription in the subsequent interphase is unknown. Her...

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Detalles Bibliográficos
Autores principales: Ramos-Alonso, Lucía, Holland, Petter, Le Gras, Stéphanie, Zhao, Xu, Jost, Bernard, Bjørås, Magnar, Barral, Yves, Enserink, Jorrit M., Chymkowitch, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942888/
https://www.ncbi.nlm.nih.gov/pubmed/36656860
http://dx.doi.org/10.1073/pnas.2210593120