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Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Mitotic entry correlates with the condensation of the chromosomes, changes in histone modifications, exclusion of transcription factors from DNA, and the broad downregulation of transcription. However, whether mitotic condensation influences transcription in the subsequent interphase is unknown. Her...
Autores principales: | Ramos-Alonso, Lucía, Holland, Petter, Le Gras, Stéphanie, Zhao, Xu, Jost, Bernard, Bjørås, Magnar, Barral, Yves, Enserink, Jorrit M., Chymkowitch, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942888/ https://www.ncbi.nlm.nih.gov/pubmed/36656860 http://dx.doi.org/10.1073/pnas.2210593120 |
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