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HER2-driven breast cancer suppression by the JNK signaling pathway

The HER2(+) subtype of human breast cancer is associated with the malignant transformation of luminal ductal cells of the mammary epithelium. The sequence analysis of tumor DNA identifies loss of function mutations and deletions of the MAP2K4 and MAP2K7 genes that encode direct activators of the JUN...

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Detalles Bibliográficos
Autores principales:	Itah, Zeynep, Chaudhry, Shanzah, Raju Ponny, Sithara, Aydemir, Ozkan, Lee, Alexandra, Cavanagh-Kyros, Julie, Tournier, Cathy, Muller, William J., Davis, Roger J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942916/ https://www.ncbi.nlm.nih.gov/pubmed/36656864 http://dx.doi.org/10.1073/pnas.2218373120

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