Merlin tumor suppressor function is regulated by PIP(2)-mediated dimerization

Neurofibromatosis Type 2 is an inherited disease characterized by Schwann cell tumors of cranial and peripheral nerves. The NF2 gene encodes Merlin, a member of the ERM family consisting of an N-terminal FERM domain, a central α-helical region, and a C-terminal domain. Changes in the intermolecular...

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Detalles Bibliográficos
Autores principales: Hennigan, Robert F., Thomson, Craig S., Stachowski, Kye, Nassar, Nicolas, Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942953/
https://www.ncbi.nlm.nih.gov/pubmed/36809290
http://dx.doi.org/10.1371/journal.pone.0281876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942953/
https://www.ncbi.nlm.nih.gov/pubmed/36809290
http://dx.doi.org/10.1371/journal.pone.0281876

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