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Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression

An in vitro model of human ovarian follicles would greatly benefit the study of female reproduction. Ovarian development requires the combination of germ cells and several types of somatic cells. Among these, granulosa cells play a key role in follicle formation and support for oogenesis. Whereas ef...

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Detalles Bibliográficos
Autores principales: Pierson Smela, Merrick D, Kramme, Christian C, Fortuna, Patrick RJ, Adams, Jessica L, Su, Rui, Dong, Edward, Kobayashi, Mutsumi, Brixi, Garyk, Kavirayuni, Venkata Srikar, Tysinger, Emma, Kohman, Richie E, Shioda, Toshi, Chatterjee, Pranam, Church, George M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943069/
https://www.ncbi.nlm.nih.gov/pubmed/36803359
http://dx.doi.org/10.7554/eLife.83291