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Exhaustion-like dysfunction of T and NKT cells in an X-linked severe combined immunodeficiency patient with maternal engraftment by single-cell analysis

Maternal engraftment is frequently present in X-linked severe combined immunodeficiency (X-SCID) patients caused by pathogenic mutations in IL2GR. However, the functional status of the engrafted cells remains unclear because of the difficulty in separately evaluating the function of the maternal and...

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Detalles Bibliográficos
Autores principales: Dong, Wei, Li, Wenyan, Zhang, Shaojin, Zeng, Xian, Qin, Qi, Fan, Huifeng, Tang, Zhonghui, Wu, Xia, Lu, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943537/
https://www.ncbi.nlm.nih.gov/pubmed/36799159
http://dx.doi.org/10.3892/ijmm.2023.5228