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Exhaustion-like dysfunction of T and NKT cells in an X-linked severe combined immunodeficiency patient with maternal engraftment by single-cell analysis
Maternal engraftment is frequently present in X-linked severe combined immunodeficiency (X-SCID) patients caused by pathogenic mutations in IL2GR. However, the functional status of the engrafted cells remains unclear because of the difficulty in separately evaluating the function of the maternal and...
Autores principales: | Dong, Wei, Li, Wenyan, Zhang, Shaojin, Zeng, Xian, Qin, Qi, Fan, Huifeng, Tang, Zhonghui, Wu, Xia, Lu, Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943537/ https://www.ncbi.nlm.nih.gov/pubmed/36799159 http://dx.doi.org/10.3892/ijmm.2023.5228 |
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