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PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells

BACKGROUND: Patatin-like phospholipase domain-containing 3 (PNPLA3) is a major susceptibility gene for nonalcoholic fatty liver disease (NAFLD), and its rs738409 (I148M) polymorphism is associated with the occurrence and progression of NAFLD. Endoplasmic reticulum (ER) stress-related hepatocyte lipo...

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Detalles Bibliográficos
Autores principales:	Chen, Yunzhi, Yan, Xuemei, Wang, Tian, Deng, Hongrong, Deng, Xiaojie, Xu, Fen, Liang, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943609/ https://www.ncbi.nlm.nih.gov/pubmed/36825197 http://dx.doi.org/10.1155/2023/2872408

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