8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury

Reactive oxygen species (ROS) are implicated in epithelial cell-state transition and deposition of extracellular matrix upon airway injury. Of the many cellular targets of ROS, oxidative DNA modification is a major driving signal. However, the role of oxidative DNA damage in modulation profibrotic p...

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Detalles Bibliográficos
Autores principales: Pan, Lang, Hao, Wenjing, Xue, Yaoyao, Wang, Ke, Zheng, Xu, Luo, Jixian, Ba, Xueqing, Xiang, Yang, Qin, Xiaoqun, Bergwik, Jesper, Tanner, Lloyd, Egesten, Arne, Brasier, Allan R, Boldogh, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943661/
https://www.ncbi.nlm.nih.gov/pubmed/36651270
http://dx.doi.org/10.1093/nar/gkac1241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943661/
https://www.ncbi.nlm.nih.gov/pubmed/36651270
http://dx.doi.org/10.1093/nar/gkac1241

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