Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies

The RNA-binding protein PURA has been implicated in the rare, monogenetic, neurodevelopmental disorder PURA Syndrome. PURA binds both DNA and RNA and has been associated with various cellular functions. Only little is known about its main cellular roles and the molecular pathways affected upon PURA...

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Detalles Bibliográficos
Autores principales: Molitor, Lena, Klostermann, Melina, Bacher, Sabrina, Merl-Pham, Juliane, Spranger, Nadine, Burczyk, Sandra, Ketteler, Carolin, Rusha, Ejona, Tews, Daniel, Pertek, Anna, Proske, Marcel, Busch, Anke, Reschke, Sarah, Feederle, Regina, Hauck, Stefanie M, Blum, Helmut, Drukker, Micha, Fischer-Posovszky, Pamela, König, Julian, Zarnack, Kathi, Niessing, Dierk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943675/
https://www.ncbi.nlm.nih.gov/pubmed/36651277
http://dx.doi.org/10.1093/nar/gkac1237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943675/
https://www.ncbi.nlm.nih.gov/pubmed/36651277
http://dx.doi.org/10.1093/nar/gkac1237

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