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Hypothesis-driven probabilistic modelling enables a principled perspective of genomic compartments
The Hi-C method has revolutionized the study of genome organization, yet interpretation of Hi-C interaction frequency maps remains a major challenge. Genomic compartments are a checkered Hi-C interaction pattern suggested to represent the partitioning of the genome into two self-interacting states a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943678/ https://www.ncbi.nlm.nih.gov/pubmed/36629266 http://dx.doi.org/10.1093/nar/gkac1258 |