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Identification and heterologous expression of the globomycin biosynthetic gene cluster

Globomycin is a cyclic lipodepsipeptide originally isolated from several Streptomyces species which displays strong and selective antibacterial activity against Gram-negative pathogens. Its mode of action is based on the competitive inhibition of the lipoprotein signal peptidase II (LspA), which is...

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Detalles Bibliográficos
Autores principales:	Oves-Costales, Daniel, Gren, Tetiana, Sterndorff, Eva Baggesgaard, Martín, Jesús, Ortiz-López, Francisco Javier, Jørgensen, Tue S., Jiang, Xinglin, Román-Hurtado, Fernando, Reyes, Fernando, Genilloud, Olga, Weber, Tilmann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2023
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943842/ https://www.ncbi.nlm.nih.gov/pubmed/36844473 http://dx.doi.org/10.1016/j.synbio.2023.02.001

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