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Integrated Single-Cell (Phospho-)Protein and RNA Detection Uncovers Phenotypic Characteristics and Active Signal Transduction of Human Antibody-Secreting Cells

Single-cell technologies are currently widely applied to obtain a deeper understanding of the phenotype of single-cells in heterogenous mixtures. However, integrated multilayer approaches including simultaneous detection of mRNA, protein expression, and intracellular phospho-proteins are still chall...

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Detalles Bibliográficos
Autores principales:	van Buijtenen, Erik, Janssen, Wout, Vink, Paul, Habraken, Maurice J.M., Wingens, Laura J.A., van Elsas, Andrea, Huck, Wilhelm T.S., van Buggenum, Jessie A.G.L., van Eenennaam, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943876/ https://www.ncbi.nlm.nih.gov/pubmed/36623694 http://dx.doi.org/10.1016/j.mcpro.2023.100492

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