Peptic Ulcer Disease Following Use of Bupropion: A Case Report

BACKGROUND: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries. Although constipation and nausea are known as side effects of Bupropion, gastric ulcer has not...

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Autores principales: Momayez Sanat, Zahra, Mohammadi Ganjaroudi, Negar, Pirsalehi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943959/
https://www.ncbi.nlm.nih.gov/pubmed/36845164
http://dx.doi.org/10.1177/11795476231153279
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author Momayez Sanat, Zahra
Mohammadi Ganjaroudi, Negar
Pirsalehi, Ali
author_facet Momayez Sanat, Zahra
Mohammadi Ganjaroudi, Negar
Pirsalehi, Ali
author_sort Momayez Sanat, Zahra
collection PubMed
description BACKGROUND: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries. Although constipation and nausea are known as side effects of Bupropion, gastric ulcer has not been previously reported. CASE PRESENTATION: In this case report a 28-year-old woman presented with a gastric ulcer 8 months after beginning depression treatment with Bupropion 150 mg once daily. Pantoprazole and Famotidine were prescribed to the patient. However, the gastric ulcer did not heal. After discontinuation of Bupropion, the gastric ulcer was treated. CONCLUSION: The present case report suggests that Bupropion may lead to peptic ulcers or this drug interferes with the treatment of gastric ulcers.
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spelling pubmed-99439592023-02-23 Peptic Ulcer Disease Following Use of Bupropion: A Case Report Momayez Sanat, Zahra Mohammadi Ganjaroudi, Negar Pirsalehi, Ali Clin Med Insights Case Rep Case Report BACKGROUND: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries. Although constipation and nausea are known as side effects of Bupropion, gastric ulcer has not been previously reported. CASE PRESENTATION: In this case report a 28-year-old woman presented with a gastric ulcer 8 months after beginning depression treatment with Bupropion 150 mg once daily. Pantoprazole and Famotidine were prescribed to the patient. However, the gastric ulcer did not heal. After discontinuation of Bupropion, the gastric ulcer was treated. CONCLUSION: The present case report suggests that Bupropion may lead to peptic ulcers or this drug interferes with the treatment of gastric ulcers. SAGE Publications 2023-02-08 /pmc/articles/PMC9943959/ /pubmed/36845164 http://dx.doi.org/10.1177/11795476231153279 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Momayez Sanat, Zahra
Mohammadi Ganjaroudi, Negar
Pirsalehi, Ali
Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title_full Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title_fullStr Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title_full_unstemmed Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title_short Peptic Ulcer Disease Following Use of Bupropion: A Case Report
title_sort peptic ulcer disease following use of bupropion: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943959/
https://www.ncbi.nlm.nih.gov/pubmed/36845164
http://dx.doi.org/10.1177/11795476231153279
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