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Synergistic Interactions between the Hypomethylating Agent Thio-Deoxycytidine and Venetoclax in Myelodysplastic Syndrome Cells

Interactions between the novel hypomethylating agent (HMA) thio-deoxycytidine (T-dCyd) and the BCL-2 antagonist ABT-199 (venetoclax) have been examined in human myelodysplastic syndrome (MDS) cells. The cells were exposed to agents alone or in combination, after which apoptosis was assessed, and a W...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoyan, Li, Lin, Nkwocha, Jewel, Sharma, Kanika, Zhou, Liang, Grant, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944092/
https://www.ncbi.nlm.nih.gov/pubmed/36810553
http://dx.doi.org/10.3390/hematolrep15010010

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