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Synergistic Interactions between the Hypomethylating Agent Thio-Deoxycytidine and Venetoclax in Myelodysplastic Syndrome Cells
Interactions between the novel hypomethylating agent (HMA) thio-deoxycytidine (T-dCyd) and the BCL-2 antagonist ABT-199 (venetoclax) have been examined in human myelodysplastic syndrome (MDS) cells. The cells were exposed to agents alone or in combination, after which apoptosis was assessed, and a W...
Autores principales: | Hu, Xiaoyan, Li, Lin, Nkwocha, Jewel, Sharma, Kanika, Zhou, Liang, Grant, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944092/ https://www.ncbi.nlm.nih.gov/pubmed/36810553 http://dx.doi.org/10.3390/hematolrep15010010 |
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