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SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis

Excessive inflammation has been implicated in autism spectrum disorder (ASD), but the underlying mechanisms have not been fully studied. SHANK3 is a synaptic scaffolding protein and mutations of SHANK3 are involved in ASD. Shank3 expression in dorsal root ganglion sensory neurons also regulates heat...

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Detalles Bibliográficos
Autores principales: Zhang, Linlin, Bang, Sangsu, He, Qianru, Matsuda, Megumi, Luo, Xin, Jiang, Yong-Hui, Ji, Ru-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944123/
https://www.ncbi.nlm.nih.gov/pubmed/36845137
http://dx.doi.org/10.3389/fimmu.2023.1124356