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SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis
Excessive inflammation has been implicated in autism spectrum disorder (ASD), but the underlying mechanisms have not been fully studied. SHANK3 is a synaptic scaffolding protein and mutations of SHANK3 are involved in ASD. Shank3 expression in dorsal root ganglion sensory neurons also regulates heat...
Autores principales: | Zhang, Linlin, Bang, Sangsu, He, Qianru, Matsuda, Megumi, Luo, Xin, Jiang, Yong-Hui, Ji, Ru-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944123/ https://www.ncbi.nlm.nih.gov/pubmed/36845137 http://dx.doi.org/10.3389/fimmu.2023.1124356 |
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