Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment

Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis, and drug resistance. However, the mechanisms underlying these associations are largely unknown. We studied several tumor types to identify the source of EMT gene expression signals and a potential mechanism o...

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Detalles Bibliográficos
Autores principales: Szabo, Peter M., Vajdi, Amir, Kumar, Namit, Tolstorukov, Michael Y., Chen, Benjamin J., Edwards, Robin, Ligon, Keith L., Chasalow, Scott D., Chow, Kin-Hoe, Shetty, Aniket, Bolisetty, Mohan, Holloway, James L., Golhar, Ryan, Kidd, Brian A., Hull, Philip Ansumana, Houser, Jeff, Vlach, Logan, Siemers, Nathan O., Saha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944255/
https://www.ncbi.nlm.nih.gov/pubmed/36810872
http://dx.doi.org/10.1038/s41598-023-28480-9

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