METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer

miR-17-5p has been found to be involved in the proliferation and metastasis of colorectal cancer (CRC), and N(6)-methyladenosine (m(6)A) modification is the most common RNA modification in eukaryotes. However, whether miR-17-5p contributes to chemotherapy sensitivity in CRC via m(6)A modification is...

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Detalles Bibliográficos
Autores principales: Sun, Kangyue, Chen, Lu, Li, Yiwen, Huang, Bing, Yan, Qun, Wu, Changjie, Lai, Qiuhua, Fang, Yuxin, Cai, Jianqun, Liu, Yongfeng, Chen, Junsheng, Wang, Xinke, Zhu, Yuxuan, Dong, Shuyu, Tan, Jieyu, Li, Aimin, Liu, Side, Zhang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944299/
https://www.ncbi.nlm.nih.gov/pubmed/36810285
http://dx.doi.org/10.1038/s41419-023-05670-x

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