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Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine

Somatostatin receptor 2 (SSTR2) is highly expressed in neuroendocrine tumors and represents as a therapeutic target. Several peptide analogs mimicking the endogenous ligand somatostatin are available for clinical use, but poor therapeutic effects occur in a subset of patients, which may be correlate...

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Detalles Bibliográficos
Autores principales:	Zhao, Jie, Fu, Hong, Yu, Jingjing, Hong, Weiqi, Tian, Xiaowen, Qi, Jieyu, Sun, Suyue, Zhao, Chang, Wu, Chao, Xu, Zheng, Cheng, Lin, Chai, Renjie, Yan, Wei, Wei, Xiawei, Shao, Zhenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944328/ https://www.ncbi.nlm.nih.gov/pubmed/36810324 http://dx.doi.org/10.1038/s41467-023-36673-z

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