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Impaired hepatic autophagy exacerbates hepatotoxin induced liver injury

Hepatotoxins activate the hepatic survival pathway, but it is unclear whether impaired survival pathways contribute to liver injury caused by hepatotoxins. We investigated the role of hepatic autophagy, a cellular survival pathway, in cholestatic liver injury driven by a hepatotoxin. Here we demonst...

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Detalles Bibliográficos
Autores principales:	Byrnes, Katherine, Bailey, Niani Tiaye, Baral, Kamal, Mercer, Arissa, Joshi, Spandan, Wahby, Nickol, Rorison, Tyler, Liu, Gang, Yin, Xiao-Ming, Khambu, Bilon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944334/ https://www.ncbi.nlm.nih.gov/pubmed/36810855 http://dx.doi.org/10.1038/s41420-023-01368-3

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