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MicroCrystalline Tyrosine-adsorbed immunotherapy
The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944405/ https://www.ncbi.nlm.nih.gov/pubmed/36254926 http://dx.doi.org/10.1097/ACI.0000000000000859 |
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author | Al Saleh, Helal Mösges, Ralph |
author_facet | Al Saleh, Helal Mösges, Ralph |
author_sort | Al Saleh, Helal |
collection | PubMed |
description | The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma. SUMMARY: MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients. |
format | Online Article Text |
id | pubmed-9944405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-99444052023-02-23 MicroCrystalline Tyrosine-adsorbed immunotherapy Al Saleh, Helal Mösges, Ralph Curr Opin Allergy Clin Immunol IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma. SUMMARY: MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients. Lippincott Williams & Wilkins 2022-12 2022-10-10 /pmc/articles/PMC9944405/ /pubmed/36254926 http://dx.doi.org/10.1097/ACI.0000000000000859 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush Al Saleh, Helal Mösges, Ralph MicroCrystalline Tyrosine-adsorbed immunotherapy |
title | MicroCrystalline Tyrosine-adsorbed immunotherapy |
title_full | MicroCrystalline Tyrosine-adsorbed immunotherapy |
title_fullStr | MicroCrystalline Tyrosine-adsorbed immunotherapy |
title_full_unstemmed | MicroCrystalline Tyrosine-adsorbed immunotherapy |
title_short | MicroCrystalline Tyrosine-adsorbed immunotherapy |
title_sort | microcrystalline tyrosine-adsorbed immunotherapy |
topic | IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944405/ https://www.ncbi.nlm.nih.gov/pubmed/36254926 http://dx.doi.org/10.1097/ACI.0000000000000859 |
work_keys_str_mv | AT alsalehhelal microcrystallinetyrosineadsorbedimmunotherapy AT mosgesralph microcrystallinetyrosineadsorbedimmunotherapy |