Cargando…

MicroCrystalline Tyrosine-adsorbed immunotherapy

The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Saleh, Helal, Mösges, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944405/
https://www.ncbi.nlm.nih.gov/pubmed/36254926
http://dx.doi.org/10.1097/ACI.0000000000000859
_version_ 1784891908253810688
author Al Saleh, Helal
Mösges, Ralph
author_facet Al Saleh, Helal
Mösges, Ralph
author_sort Al Saleh, Helal
collection PubMed
description The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma. SUMMARY: MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients.
format Online
Article
Text
id pubmed-9944405
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-99444052023-02-23 MicroCrystalline Tyrosine-adsorbed immunotherapy Al Saleh, Helal Mösges, Ralph Curr Opin Allergy Clin Immunol IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. RECENT FINDINGS: In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma. SUMMARY: MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients. Lippincott Williams & Wilkins 2022-12 2022-10-10 /pmc/articles/PMC9944405/ /pubmed/36254926 http://dx.doi.org/10.1097/ACI.0000000000000859 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush
Al Saleh, Helal
Mösges, Ralph
MicroCrystalline Tyrosine-adsorbed immunotherapy
title MicroCrystalline Tyrosine-adsorbed immunotherapy
title_full MicroCrystalline Tyrosine-adsorbed immunotherapy
title_fullStr MicroCrystalline Tyrosine-adsorbed immunotherapy
title_full_unstemmed MicroCrystalline Tyrosine-adsorbed immunotherapy
title_short MicroCrystalline Tyrosine-adsorbed immunotherapy
title_sort microcrystalline tyrosine-adsorbed immunotherapy
topic IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944405/
https://www.ncbi.nlm.nih.gov/pubmed/36254926
http://dx.doi.org/10.1097/ACI.0000000000000859
work_keys_str_mv AT alsalehhelal microcrystallinetyrosineadsorbedimmunotherapy
AT mosgesralph microcrystallinetyrosineadsorbedimmunotherapy