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Comprehensive Kinase Activity Profiling Revealed the Kinase Activity Patterns Associated with the Effects of EGFR Tyrosine Kinase Inhibitor Therapy in Advanced Non-Small-Cell Lung Cancer Patients with Sensitizing EGFR Mutations

EGFR mutations are strong predictive markers for EGFR tyrosine kinase inhibitor (EGFR-TKI) therapy in patients with non-small-cell lung cancer (NSCLC). Although NSCLC patients with sensitizing EGFR mutations have better prognoses, some patients exhibit worse prognoses. We hypothesized that various a...

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Detalles Bibliográficos
Autores principales:	Noguchi, Rei, Yoshimura, Akihiro, Uchino, Junji, Takeda, Takayuki, Chihara, Yusuke, Ota, Takayo, Hiranuma, Osamu, Gyotoku, Hiroshi, Takayama, Koichi, Kondo, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944465/ https://www.ncbi.nlm.nih.gov/pubmed/36810562 http://dx.doi.org/10.3390/proteomes11010006

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