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Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease

Ophthalmic non-motor impairments are common in Parkinson’s disease patients, from the onset of the neurodegenerative disease and even prior to the development of motor symptoms. This is a very crucial component of the potential for early detection of this disease, even in its earliest stages. Since...

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Detalles Bibliográficos
Autores principales: Stuparu, Alina Zorina, Jurja, Sanda, Stuparu, Alexandru Floris, Axelerad, Any
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944508/
https://www.ncbi.nlm.nih.gov/pubmed/36810467
http://dx.doi.org/10.3390/neurolint15010012
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author Stuparu, Alina Zorina
Jurja, Sanda
Stuparu, Alexandru Floris
Axelerad, Any
author_facet Stuparu, Alina Zorina
Jurja, Sanda
Stuparu, Alexandru Floris
Axelerad, Any
author_sort Stuparu, Alina Zorina
collection PubMed
description Ophthalmic non-motor impairments are common in Parkinson’s disease patients, from the onset of the neurodegenerative disease and even prior to the development of motor symptoms. This is a very crucial component of the potential for early detection of this disease, even in its earliest stages. Since the ophthalmological disease is extensive and impacts all extraocular and intraocular components of the optical analyzer, a competent assessment of it would be beneficial for the patients. Because the retina is an extension of the nervous system and has the same embryonic genesis as the central nervous system, it is helpful to investigate the retinal changes in Parkinson’s disease in order to hypothesize insights that may also be applicable to the brain. As a consequence, the detection of these symptoms and signs may improve the medical evaluation of PD and predict the illness’ prognosis. Another valuable aspect of this pathology is the fact that the ophthalmological damage contributes significantly to the decrease in the quality of life of patients with Parkinson’s disease. We provide an overview of the most significant ophthalmologic impairments associated with Parkinson’s disease. These results certainly constitute a large number of the prevalent visual impairments experienced by PD patients.
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spelling pubmed-99445082023-02-23 Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease Stuparu, Alina Zorina Jurja, Sanda Stuparu, Alexandru Floris Axelerad, Any Neurol Int Review Ophthalmic non-motor impairments are common in Parkinson’s disease patients, from the onset of the neurodegenerative disease and even prior to the development of motor symptoms. This is a very crucial component of the potential for early detection of this disease, even in its earliest stages. Since the ophthalmological disease is extensive and impacts all extraocular and intraocular components of the optical analyzer, a competent assessment of it would be beneficial for the patients. Because the retina is an extension of the nervous system and has the same embryonic genesis as the central nervous system, it is helpful to investigate the retinal changes in Parkinson’s disease in order to hypothesize insights that may also be applicable to the brain. As a consequence, the detection of these symptoms and signs may improve the medical evaluation of PD and predict the illness’ prognosis. Another valuable aspect of this pathology is the fact that the ophthalmological damage contributes significantly to the decrease in the quality of life of patients with Parkinson’s disease. We provide an overview of the most significant ophthalmologic impairments associated with Parkinson’s disease. These results certainly constitute a large number of the prevalent visual impairments experienced by PD patients. MDPI 2023-01-26 /pmc/articles/PMC9944508/ /pubmed/36810467 http://dx.doi.org/10.3390/neurolint15010012 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stuparu, Alina Zorina
Jurja, Sanda
Stuparu, Alexandru Floris
Axelerad, Any
Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title_full Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title_fullStr Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title_full_unstemmed Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title_short Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson’s Disease
title_sort narrative review concerning the clinical spectrum of ophthalmological impairments in parkinson’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944508/
https://www.ncbi.nlm.nih.gov/pubmed/36810467
http://dx.doi.org/10.3390/neurolint15010012
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