Cargando…

In Silico Dosimetry Study of Tc99m-Tetrofosmin in Children Using a Novel PBPK Model in Humans Built from SPECT Imaging Data

PURPOSE: The aim of this work is to develop a Physiologically Based Pharmacokinetic model (PBPK) for the radiopharmaceutical Tc99m-Tetrofosmin in humans, from literature SPECT imaging data, to carry out in-silico dosimetry studies in children and extrapolate dosing. METHODS: A whole body PBPK model...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaikousidis, Christos, Dokoumetzidis, Aristides
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944701/ https://www.ncbi.nlm.nih.gov/pubmed/36261760 http://dx.doi.org/10.1007/s11095-022-03412-w

Ejemplares similares

Midventricular Takotsubo Cardiomyopathy on (99m)Tc-tetrofosmin and (123)I-BMIPP SPECT
por: Ito, Shimpei, et al.
Publicado: (2017)

Evaluation of Simultaneous Dual-radioisotope SPECT Imaging Using (18)F-fluorodeoxyglucose and (99m)Tc-tetrofosmin
por: Takahashi, Yasuyuki, et al.
Publicado: (2016)

Systematic evaluation of (99m)Tc-tetrofosmin versus (99m)Tc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT
por: Vrachimis, Alexis, et al.
Publicado: (2012)

Effectiveness of (99m)Tc-tetrofosmin for assessment of heart functions in micropigs
por: Lee, Min Young, et al.
Publicado: (2007)

Dual radioisotopes simultaneous SPECT of (99m)Tc-tetrofosmin and (123)I-BMIPP using a semiconductor detector
por: Takahashi, Yasuyuki, et al.
Publicado: (2015)

Myocardial perfusion imaging with (99 m)Tc - tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: a case-control study
por: Sioka, Chrissa, et al.
Publicado: (2011)

Implementation of non-linear mixed effects models defined by fractional differential equations
por: Kaikousidis, Christos, et al.
Publicado: (2023)

Comparison of (99m)Tc-Tetrofosmin and (99m)Tc-Sestamibi Uptake in Glioma Cell Lines: The Role of P-Glycoprotein Expression
por: Alexiou, George A., et al.
Publicado: (2014)

(99m)Tc-Tetrofosmin Uptake Correlates with the Sensitivity of Glioblastoma Cell Lines to Temozolomide
por: Alexiou, George A., et al.
Publicado: (2017)

(18)F-Fluorocholine PET/CT in the assessment of primary hyperparathyroidism compared with (99m)Tc-MIBI or (99m)Tc-tetrofosmin SPECT/CT: a prospective dual-centre study in 100 patients
por: Beheshti, Mohsen, et al.
Publicado: (2018)

Inhibition of the Hepatic Uptake of (99m)Tc-Tetrofosmin Using an Organic Cation Transporter Blocker
por: Nishi, Kodai, et al.
Publicado: (2021)

[(99m)Tc]Tc-iFAP Radioligand for SPECT/CT Imaging of the Tumor Microenvironment: Kinetics, Radiation Dosimetry, and Imaging in Patients
por: Coria-Domínguez, Luis, et al.
Publicado: (2022)

Sensitivity and Specificity of Dual-Isotope (99m)Tc-Tetrofosmin and (123)I Sodium Iodide Single Photon Emission Computed Tomography (SPECT) in Hyperparathyroidism
por: Sommerauer, Michael, et al.
Publicado: (2015)

Parathyroid adenoma detected with (99m)Tc-tetrofosmin dual-phase scintigraphy: a case report
por: Romanidis, Konstantinos, et al.
Publicado: (2014)

Imaging of Primitive Neuroectodermal Tumor (PNET) by Technetium-99m Tetrofosmin
por: Karanikas, Georgios, et al.
Publicado: (2001)

The assessment of left ventricular mechanical dyssynchrony from gated (99m)Tc-tetrofosmin SPECT and gated (18)F-FDG PET by QGS: a comparative study
por: Lehner, Sebastian, et al.
Publicado: (2021)

Donepezil Brain and Blood Pharmacokinetic Modeling after Nasal Film and Oral Solution Administration in Mice
por: Kaikousidis, Christos, et al.
Publicado: (2023)

Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism
por: Sager, Sait, et al.
Publicado: (2014)

Optimization of SPECT/CT imaging protocols for quantitative and qualitative (99m)Tc SPECT
por: Kupitz, Dennis, et al.
Publicado: (2021)

Reverse redistribution-like change on dipyridamole-stress (99m)Tc-tetrofosmin imaging in a patient with angiographically mild coronary artery stenosis
por: Aikawa, Tadao, et al.
Publicado: (2021)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

Role of (99m)Tc-ECD SPECT in the Management of Children with Craniosynostosis
por: Barik, Mayadhar, et al.
Publicado: (2014)

Evaluation of Radiation dosimetry of (99m)Tc-HYNIC-PSMA and imaging in prostate cancer
por: Zhang, Jianping, et al.
Publicado: (2020)

A simplified wall-based model for regional innervation/perfusion mismatch assessed by cardiac (123)I-mIBG and rest (99m)Tc-tetrofosmin SPECT to predict arrhythmic events in ischaemic heart failure( )
por: Verschure, Derk O, et al.
Publicado: (2021)

[(99m)Tc]Tc-Labeled Plectin-Targeting Peptide as a Novel SPECT Probe for Tumor Imaging
por: Gong, Jiali, et al.
Publicado: (2022)

Limitations of Tc99m-MIBI-SPECT Imaging Scans in Persistent Primary Hyperparathyroidism
por: Witteveen, Janneke E., et al.
Publicado: (2010)

Correlation between delayed-enhancement magnetic resonance and nitrate myocardial Tc-99m tetrofosmin scintigraphy in myocardial infarction: a case report
por: Feola, Mauro, et al.
Publicado: (2007)

Clinical impact of (99m)Tc-MAA SPECT/CT-based dosimetry in the radioembolization of liver malignancies with (90)Y-loaded microspheres
por: Garin, Etienne, et al.
Publicado: (2015)

Impact of the dosimetry approach on the resulting (90)Y radioembolization planned absorbed doses based on (99m)Tc-MAA SPECT-CT: is there agreement between dosimetry methods?
por: Morán, Verónica, et al.
Publicado: (2020)

Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
por: Liepe, Knut, et al.
Publicado: (2022)

[(18)F]PSMA-1007 PET is comparable to [(99m)Tc]Tc-DMSA SPECT for renal cortical imaging
por: Valind, Kristian, et al.
Publicado: (2023)

Dopamine Transporter Imaging Using (99m)Tc-TRODAT-1 SPECT in Parkinson’s Disease
por: Bor-Seng-Shu, Edson, et al.
Publicado: (2014)

Degree of dopaminergic degeneration measured by (99m)Tc-TRODAT-1 SPECT/CT imaging
por: Lin, Ling, et al.
Publicado: (2018)

(99m)Tc-TRODAT-1 SPECT Imaging in Early and Late Onset Parkinson’s Disease
por: Sasannezhad, Payam, et al.
Publicado: (2017)

Radioactive Labeling of Milk-Derived Exosomes with (99m)Tc and In Vivo Tracking by SPECT Imaging
por: González, María Isabel, et al.
Publicado: (2020)

(99m)Tc-HMPAO SPECT imaging reveals brain hypoperfusion during status epilepticus
por: Bascuñana, Pablo, et al.
Publicado: (2021)

Advances in Clinical Oncology Research on (99m)Tc-3PRGD2 SPECT Imaging
por: Xiao, Liming, et al.
Publicado: (2022)

(99m)Tc-Labeled FAPI SPECT Imaging in Idiopathic Pulmonary Fibrosis: Preliminary Results
por: Liu, Yu, et al.
Publicado: (2023)

Assessment of Interobserver Agreement in the Interpretation of (99m)Tc-PYP SPECT Imaging of Cardiac Amyloidosis
por: Imakhanova, Aiganym, et al.
Publicado: (2023)

Patient-specific dosimetry of (99m)Tc-HYNIC-Tyr(3)-Octreotide in children
por: Hou, Xinchi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ritvn3a952i32h74htvnl58ek8