Cargando…

LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide

Myocardial fibrosis confers an almost threefold mortality risk in heart disease. There are no prognostic therapies and novel therapeutic targets are needed. Many thousands of unannotated small open reading frames (smORFs) have been identified across the genome with potential to produce micropeptides...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quaife, N. M., Chothani, S., Schulz, J. F., Lindberg, E. L., Vanezis, K., Adami, E., O’Fee, K., Greiner, J., Litviňuková, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S. A., Barton, P. J. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944705/ https://www.ncbi.nlm.nih.gov/pubmed/35759180 http://dx.doi.org/10.1007/s12265-022-10288-z

Ejemplares similares

Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide
por: Quaife, N. M., et al.
Publicado: (2022)

The long non-coding RNA LINC01013 enhances invasion of human anaplastic large-cell lymphoma
por: Chung, I-Hsiao, et al.
Publicado: (2017)

linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells
por: Tornini, Valerie A, et al.
Publicado: (2023)

Micropeptide
por: Sousa, Maria E., et al.
Publicado: (2018)

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013
por: Yang, Haoqing, et al.
Publicado: (2020)

Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve
por: Chignon, Arnaud, et al.
Publicado: (2022)

Micropeptides translated from putative long non-coding RNAs: Micropeptides translated from lncRNAs
por: Li, Junhong, et al.
Publicado: (2022)

Lena Ho: Micropeptides under the spotlight
por: Morgado-Palacin, Lucia
Publicado: (2022)

deltaTE: Detection of Translationally Regulated Genes by Integrative Analysis of Ribo‐seq and RNA‐seq Data
por: Chothani, Sonia, et al.
Publicado: (2019)

LINC complex alterations in DMD and EDMD/CMT fibroblasts
por: Taranum, Surayya, et al.
Publicado: (2012)

The LINC00961 transcript and its encoded micropeptide, small regulatory polypeptide of amino acid response, regulate endothelial cell function
por: Spencer, Helen L, et al.
Publicado: (2020)

Machine learning for the micropeptide encoded by LINC02381 regulates ferroptosis through the glucose transporter SLC2A10 in glioblastoma
por: Jiang, Lan, et al.
Publicado: (2022)

LINC00998‐encoded micropeptide SMIM30 promotes the G1/S transition of cell cycle by regulating cytosolic calcium level
por: Yang, Jin‐E, et al.
Publicado: (2022)

Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome
por: Ramirez-Martinez, Andres, et al.
Publicado: (2022)

IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues
por: Widjaja, Anissa A., et al.
Publicado: (2022)

The micropeptide LEMP plays an evolutionarily conserved role in myogenesis
por: Wang, Lantian, et al.
Publicado: (2020)

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation
por: Makarewich, Catherine A., et al.
Publicado: (2018)

Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction
por: Sweeney, Mark, et al.
Publicado: (2023)

Emerging role of long noncoding RNA-encoded micropeptides in cancer
por: Ye, Mujie, et al.
Publicado: (2020)

Minireview: Novel Micropeptide Discovery by Proteomics and Deep Sequencing Methods
por: Tharakan, Ravi, et al.
Publicado: (2021)

Viral Infection Identifies Micropeptides Differentially Regulated in smORF-Containing lncRNAs
por: Razooky, Brandon S., et al.
Publicado: (2017)

Deep learning models will shape the future of stem cell research
por: Ouyang, John F., et al.
Publicado: (2023)

The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy
por: Yan, Youchen, et al.
Publicado: (2021)

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age
por: Kragness, S., et al.
Publicado: (2022)

Response to “Facial nerve palsy following the administration of COVID-19 mRNA vaccines: analysis of a self-reporting database” by Sato et al
por: O'Fee, John R., et al.
Publicado: (2022)

Spontaneous Coronary Artery Dissection Causing Cardiac Arrest in a Post-Partum Patient – A Case Report
por: Kim, Daniel Hoan, et al.
Publicado: (2021)

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy
por: Makarewich, Catherine A, et al.
Publicado: (2018)

IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
por: Adami, Eleonora, et al.
Publicado: (2021)

Tumor-derived exosomal linc00881 induces lung fibroblast activation and promotes osteosarcoma lung migration
por: Chang, Xinyu, et al.
Publicado: (2023)

MiPepid: MicroPeptide identification tool using machine learning
por: Zhu, Mengmeng, et al.
Publicado: (2019)

Translation and natural selection of micropeptides from long non-canonical RNAs
por: Patraquim, Pedro, et al.
Publicado: (2022)

A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation
por: Lin, Yi-Fang, et al.
Publicado: (2019)

Sight of parasitoid wasps accelerates sexual behavior and upregulates a micropeptide gene in Drosophila
por: Ebrahim, Shimaa A. M., et al.
Publicado: (2021)

Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success
por: Immarigeon, Clément, et al.
Publicado: (2021)

LINC01605 knockdown induces apoptosis in human Tenon's capsule fibroblasts by inhibiting autophagy
por: Shang, Qifei, et al.
Publicado: (2022)

Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
por: Schiemann, Ronja, et al.
Publicado: (2022)

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals
por: Whiffin, Nicola, et al.
Publicado: (2020)

Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals
por: Whiffin, Nicola, et al.
Publicado: (2021)

Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump
por: Cleary, Sean R., et al.
Publicado: (2022)

Functional Micropeptides Encoded by Long Non-Coding RNAs: A Comprehensive Review
por: Pan, Jianfeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hqhkaeca6oh79r0e9187av71q4