Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia

Glioma is the most common malignant tumor of the central nervous system in adults. The tumor microenvironment (TME) is related to poor prognosis in glioma patients. Glioma cells could sort miRNA into exosomes to modify TME. And hypoxia played an important role in this sorting process, but the mechan...

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Detalles Bibliográficos
Autores principales: Guo, Qindong, Fan, Yang, Wang, Qingtong, Li, Boyan, Qiu, Wei, Qi, Yanhua, Pan, Ziwen, Zhang, Shouji, Zhao, Shulin, Yang, Kehui, Xu, Hao, Li, Ming, Gao, Zijie, Xu, Jianye, Wang, Huizhi, Wang, Shaobo, Tang, Qilin, Qiu, Jiawei, Guo, Xing, Deng, Lin, Zhang, Ping, Zhao, Rongrong, Xue, Hao, Wang, Chengwei, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944918/
https://www.ncbi.nlm.nih.gov/pubmed/36810326
http://dx.doi.org/10.1038/s41419-023-05663-w

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