Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients

A highly sensitive and highly multiplexed quantification technique for nucleic acids is necessary to predict and evaluate cancer treatment by liquid biopsy. Digital PCR (dPCR) is a highly sensitive quantification technique, but conventional dPCR discriminates multiple targets by the color of the flu...

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Detalles Bibliográficos
Autores principales: Tanaka, Junko, Nakagawa, Tatsuo, Harada, Kunio, Morizane, Chigusa, Tanaka, Hidenori, Shiba, Satoshi, Ohba, Akihiro, Hijioka, Susumu, Takai, Erina, Yachida, Shinichi, Kamura, Yoshio, Ishida, Takeshi, Yokoi, Takahide, Uematsu, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944920/
https://www.ncbi.nlm.nih.gov/pubmed/36810451
http://dx.doi.org/10.1038/s41598-023-30131-y

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